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Dáil Éireann díospóireacht -
Thursday, 21 Nov 2002

Vol. 557 No. 6

Written Answers. - Vaccination Programme.

Finian McGrath

Ceist:

69 Mr. F. McGrath asked the Minister for Health and Children the number of children who have contracted bowel disease over the past ten years; the number of children who have had their bowel removed over the same period; if nurses and the medical profession have to have the MMR vaccination if they are looking after children; the reason there is no choice available as mothers are technically being bullied into getting the MMR as a single injection rather than three single injections; and if he will make a statement on the matter. [22795/02]

The MMR vaccine is available under the primary childhood immunisation programme. The primary childhood immunisation programme provides for the immunisation of children against a range of potentially serious infectious diseases. Under the programme parents may have their children immunised free of charge by the general practitioner of their choice. The schedule of immunisation is in accordance with the recommendations of the immunisation advisory committee of the Royal College of Physicians of Ireland, RCPI.

There is no provision for children to receive separate measles, mumps or rubella vaccinations under this programme. Information provided by the Irish Medicines Board, which has responsibility for licensing all pharmaceutical products in Ireland, indicates that individual vaccines for measles, mumps and rubella are currently licensed in Ireland, however, only single dose rubella vaccine is marketed in Ireland.

There are sound public health reasons for not administering the MMR as separate vaccines. First, the scientific evidence does not support a link between MMR and autism or inflammatory bowel disease. There is no evidence that administering the three components of MMR as separate vaccines is safer. The immune system is well capable of responding to the small number of components in the MMR vaccine and there is no evidence that the component parts of the MMR vaccine interfere with each other. In any event, vaccines are designed to strengthen the immune system and not weaken it.

If the vaccines were to be given separately, this would also mean a child requiring a total of six injections to complete the course instead of two which could also mean an increased risk of local reactions at the injection site. The practical aspect of giving six injections would mean that children are unprotected for a greater period of time from these diseases and, therefore, at significantly greater risk of contracting these infections. The protracted time involved in administering the vaccines would result in the diseases in question circulating in the community for longer. Unprotected children would, therefore, be at greater risk of catching these infections. This would include younger children – that is, children below the age of 15 months – and children who are immuno-suppressed.

Most countries implement a two dose MMR vaccine programme and this policy has been very successful in controlling measles where high uptake of the vaccine has been achieved. My primary concern and that of my Department in relation to immunisation is that the vaccines in use are safe and effective.

The international consensus from professional bodies and international organisations is that MMR is a safe and effective vaccine and that existing research and medical evidence does not support a causal link between MMR vaccine and autism or inflammatory bowel disease. This consensus is based on large-scale epidemiological studies and more specific studies done in the laboratory setting. The institutions include the Medical Research Council Expert Committee UK, the British Committee on Safety of Medicines, the Centres for Disease Control and Prevention, CDC, USA, the American Academy of Paediatr ics, the World Health Organisation, and UK professional organisations.
Recent studies by the United States Institute of Medicine concluded that there was no link between the vaccine and autism or inflammatory bowel disease. A large Finnish study involving 1.8 million individuals demonstrated that no case of inflammatory bowel disease or autism was linked to the MMR vaccine. A similar Swedish study found no increase in cases of autism in the ten years during which MMR vaccine was introduced. A recent UK study where researchers analysed 2,000 studies from 180 countries found no evidence of a causal link between MMR vaccine and autism or inflammatory bowel disease. In recent weeks, theNew England Journal of Medicine published details of a study of more than 500,000 children born in Denmark between January 1991 and December 1998 which indicated that the risk of autism was the same for children regardless of whether they were vaccinated with MMR.
In a statement on 14 November 2002, the Irish Medicines Board advised parents and doctors against the use of unlicensed single component measles, mumps and rubella vaccines. Specifically, the IMB has concerns about the manufacture, testing and storage of the single component vaccines Pavivac – single mumps vaccine – and Movivac – single measles vaccine – as there is insufficient information about these two vaccines to be able to offer any assurances about the safety, quality or efficacy of these products which are manufactured by Sevapharma in the Czech Republic. The IMB's counterpart in the UK, the Medicines Control Agency, has issued similar recommendations pending further investigation. The IMB further stated that the two combined MMR vaccines – MMR II and Priorix – cur rently in use in the childhood immunisation programme in Ireland have undergone rigorous assessment and are licensed by the IMB.
I take this opportunity to urge all parents to have their children immunised against the diseases covered by the childhood immunisation programme to ensure that both children and the population generally have maximum protection against the disease concerned. General practitioners are aware of the contra-indications to the recommended childhood immunisations and parents should discuss any concerns they may have with their general practitioner before making a decision about their child's immunisation.
The immunisation advisory committee of the Royal College of Physicians of Ireland recommends that all health care workers born after 1978 should have proof of immunity to measles, mumps and rubella or evidence of two doses of MMR. Vaccination should be considered for non-immune health workers working with pregnant women or those working in paediatric, obstetric or emergency departments.
The following table indicates the number of hospital discharges for publicly funded acute hospitals for the period 1995-2001 for diseases of the bowel and for the number of bowel removal procedures undertaken. The data are derived from the hospital in-patient enquiry – HIPE – system and relate to children under the age of 15 years. It should be noted that these figures refer to hospital episodes rather than to individuals. It should also be noted that prior to 1995 the HIPE system did not have comprehensive coverage of all cases within hospitals and that since 1995 a number of additional hospitals are now submitting data to HIPE.
Hospital Discharges for Bowel Disease and Bowel Removal Procedures for Children Under 15 Years of Age, 1995-2001

Bowel Disease Regional Enteritis

UlcerativeColitis

Non-infectious Gastroenteritis & Colitis

Bowel Removal Partial Excision of Bowel

Total Intraabdominal Colectomy

1995

35

44

2,421

29

5

1996

42

46

2,606

34

3

1997

59

48

2,663

49

3

1998

33

52

2,778

44

6

1999

44

36

2,198

39

2

2000

42

35

3,184

44

6

2001

53

32

2,971

38

2

Source: HIPE Data 1995-2001
These data refer to cases of bowel disease and procedures involving bowel excision and are not associated with vaccination.
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