I propose to take Questions Nos. 416, 459 and 532 together.
The HSE has statutory responsibility for medicine pricing and reimbursement decisions, in accordance with the Health (Pricing and Supply of Medical Goods) Act 2013. The Act specifies the criteria to be applied in the making of reimbursement decisions which include the clinical and cost effectiveness of the product, the opportunity cost and the impact on resources that are available to the HSE.
I can advise the Deputy that the HSE has approved the application for reimbursement of Osimertinib (Tagrisso) for non small cell lung cancer, the specific recommendation is for second-line use for the treatment of adult patients with locally advanced or metastatic EGFR T790M mutation-positive non small cell lung cancer.
Reimbursement will commence from 1 July 2020.